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A life-saving coronavirus drug has been found

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Dexamethasone is a cheap and widely available drug that can save the lives of patients who have become seriously ill with coronavirus, according to new research.

UK experts are calling this a major breakthrough in the fight against the deadly virus. The low-dose steroid treatment can cut the risk of death by a third for patients on ventilators. For those on oxygen, it can cut deaths by a fifth, the BBC reports. 

The drug is part of the world’s biggest trial that is testing existing treatments to see if they could also successfully work on the coronavirus. 

Research has shown that if this drug had been used to treat patients in the UK from the start of the coronavirus pandemic, up to 5,000 lives could have been saved.

The drug is also cheap enough meaning it could have huge benefits to poorer countries that are struggling with high numbers of COVID-19 patients.

Trust “Tru” Katsande/Unsplash

Most patients (19 out of 20) recover from coronavirus without being admitted to hospital, but some of those that do need oxygen or mechanical ventilation. It is these high-risk patients that dexamethasone could help. 

The drug is currently used to reduce inflammation in a range other conditions. It also appears to help stop some of the damage that happens when the body’s immune system goes into overdrive. This over-reaction is called cytokine storm and can be deadly. 

In the trial at Oxford University, 2,000 hospital patients were given dexamethasone compared to more than 4,000 who didn’t receive it.

For patients on ventilators, it cut the risk of death from 40% to 28%. For patients needing oxygen, it cut the risk of death from 25% to 20%.

Chief investigator Prof Peter Horby said: “This is the only drug so far that has been shown to reduce mortality – and it reduces it significantly. It’s a major breakthrough.”

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Lead researcher, Prof Martin Landray says the findings suggest that for every eight patients on ventilators you could save one life. For patients on oxygen, you could save one life for approx. every 20-25 people treated with the drug.

Pro Landray said: “There is a clear, clear benefit. The treatment is up to 10 days of dexamethasone and it costs about £5 per patient. So essentially it costs £35 to save a life. This is a drug that is globally available.”

Dexamethasone does not appear to help people with milder symptoms of coronavirus – those who don’t need help with their breathing.

Dexamethasone has been used since the early 1960s, treating a wide range of conditions and its new use for coronavirus could have massive impacts across the world. 

Currently, half of all COVID-19 patients require a ventilator do not survive, Dexamethasone could cut this number by a third which would have a massive impact. 

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Stagecoach hiring over 100 new bus drivers for Bee Network with £31k salaries

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Stagecoach

Stagecoach Manchester is hiring over 100 new bus drivers to work from its Oldham depot, following the second phase of the Bee Network launch in March.

You can apply for a range of roles, from positions with no experience required to fully qualified bus drivers.

Successful applicants will receive full training as part of the job, and trainees will get paid to train. Then after only 12 months’ service at Stagecoach, drivers can expect to earn up to £16 per hour, which equates to £31.6K per year, before overtime.

As well as that, drivers that already hold a PCV licence may be eligible to receive a £1,200 joining bonus.

Stagecoach

There’s also a host of other benefits available to all Stagecoach employees, like 28 days paid holiday, generous pension and free Stagecoach bus travel for successful applicants and a companion.

Rob Jones, Managing Director at Stagecoach Manchester said: “Expanding our offering in Oldham means we’ll be investing more in the economy and supporting our local community, as well as strengthening our workforce.

“Whether you’re looking for a career change or you’re a fully qualified, experienced bus driver, there’s a role for everyone here in Oldham.

“We’re looking for personable and dedicated drivers who are ready to help us build on the success of the Bee Network and connect the people of Oldham and Greater Manchester with the places and people that are important to them.”

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Phil Cornwall, bus driver at Stagecoach Manchester, said: “I’ve been a driver at Stagecoach for 25 years and I couldn’t recommend it more.

“From the perks to the people to the passengers, it really is a great place to work.”

To apply, head to the Stagecoach website HERE.

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Two men charged with murder after torso discovered in Salford nature reserve

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Greater Manchester Police

Two men have now been charged with murder, following the discovery of a human torso in Kersal Dale.

As well as that, more suspected human remains were also discovered this morning, Monday April 29th, in an alleyway close to the railway lines off Worsley Road, Eccles.

This follows earlier discoveries of human remains over the past three weeks, at Kersal Dale, Blackleach Reservoir and Colliery Wood, all in Salford.

Greater Manchester Police


Michal Jaroslaw Polchowski (25/04/1956) and Marcin Majerkiewicz (10/04/1982) both of Worsley Road, Eccles, have been charged with murder.

They are set to appear at Tameside Magistrates Court this afternoon.

While formal identification is still ongoing, the remains found at Kersal Dale are believed to be of a local man in his 60s. The remains found at the other three locations are still to be tested, but police are confident they belong to the same victim.

ACC Sarah Jackson said: “We have had large numbers of officers, staff and specialists working diligently on this investigation over the last three weeks. It has been very much a large, collective effort, with the victim and family at the heart of it from the outset.

“We have specially trained officers deployed to support the family as they come to terms with this tragic news. They are aware of this morning’s further discovery and will continue to be kept up to date with how we are progressing.

“Despite the charges brought today, our work is far from over.

“The scenes we already have established in Bury and Salford will remain in place for much of this week whilst our searches and enquiries continue. Local officers will continue to patrol the impacted areas to provide reassurance.

“We will continue following every line of enquiry to recover and reunite the victim with his family, bringing a dignified end to this terrible scenario.

“I’d like to thank the communities of Salford and beyond for their cooperation throughout this investigation. I know this incident has come as a shock, and the support we’ve had from those in the area is very much appreciated.”

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More human remains discovered in Greater Manchester as police identify victim

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N Chadwick / Geograph

Detectives investigating the discovery of a torso in Kersal Dale have found more human remains around Greater Manchester.

GMP released a statement on the weekend, revealing they had opened four scenes for extensive searches – one of them at a warehouse in Bury, and three in Salford.

Searches took place at Blackleach reservoir, where human remains were found, and a dog walker found a package containing human remains at Colliery Wood.

Officers believe they have now identified the man, who they believe to be a man in his 60s that lived in Salford, and his family have been informed.

Two suspects have already been arrested in connection with the murder probe, with officers saying they are thought to have lived with the victim.

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Detective Superintendent Lewis Hughes, Senior Investigating Officer for this investigation, said in a statement at Blackleach reservoir yesterday, Sunday April 28th: “We have continued to make significant progress in our investigation into human remains being found in Kersal earlier this month.

“From day one, our priority has been to identify the man and his family so that we can give them the support and the answers that they need.

“Thanks to meticulous forensic work, we are now confident we have identified the man. Formal identification hasn’t yet taken place, but we believe he is a man in his 60s and lived in Salford.

“Specially-trained family liaison officers have met with his family this afternoon to give them the devastating news, and we will do all that we can to support them at this awful time.

“We believe he is known to the two suspects we have in custody. They have remained in custody for questioning over the weekend, as we work to establish how the victim met this tragic outcome.”

He continued: “We have painstakingly worked to follow up every line of inquiry in this investigation. Over the last couple of days, we have acted on information and had four scenes in place for extensive searches – one of them is at a warehouse in Bury, and three of them are in Salford, including here at Blackleach reservoir.

“Today, we have found some human remains at the reservoir here, and last night a dog walker found a package containing human remains at Colliery Wood. Forensic tests will continue to establish whose remains these are, but we are very confident that this is also the victim in our investigation.

“We have also been searching a house in Winton where we believe the victim and the two suspects lived. We have found evidence that the victim is likely to have died there – most likely in late March.

“While this is significant progress, we know there is still some way to go to complete this investigation. I also recognise details of this case will have been distressing for the people of Salford and beyond – including the officers that are diligently working on this investigation, and most importantly the man’s heartbroken family.

“Local officers will continue to patrol the affected areas, and we will provide updates when we have more information.”

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